Dengue is the most important emerging tropical viral disease of humans in the world today. It is estimated that there are between 50 & 100 million cases of dengue fever (DF) and about 5,00,000 cases of Dengue Haemorrhagic fever (DHF) each year which required hospitalization. Over the last 10 – 15 years, DF/DHF has become a leading cause of hospitalization and death among children in the South East Asia Region of WHO, following diarrhoeal diseases and acute respiratory infections. All four dengue virus (Den 1, 2, 3, 4) infections may be
asymptomatic or may lead to undifferentiated fever, dengue fever (DF), or dengue haemorrhagic fever (DHF) with plasma leakage that may lead to hypovolemic shock Dengue Shock Syndrome (DSS).